Reciprocal communication of perivascular epicardial adipose tissue and coronary atherogenesis

Perivascular adipose tissue and coronary vascular disease.

Coronary perivascular adipose tissue is a naturally occurring adipose tissue depot that normally surrounds the major coronary arteries on the surface of the heart. Although originally thought to promote vascular health and integrity, there is a growing body of evidence to support that coronary perivascular adipose tissue displays a distinct phenotype relative to other adipose depots and is capa...

Epicardial adipose tissue and atherogenesis: EAT your heart out.

Cardiovascular disease (CVD) is increasingly recognized among HIV-infected patients, and carefully performed cohort studies show increased relative risk ratios of 1.5–2.0 [1,2]. Moreover, these studies suggest that traditional risk factors, while accounting for some degree of this increase in relative risk, do not account for all or even a major portion of the increased risk [1]. Insights into ...

Epicardial Adipose Tissue Reflects the Presence of Coronary Artery Disease: Comparison with Abdominal Visceral Adipose Tissue

Accumulation of visceral adipose tissue is associated with a risk of coronary artery disease (CAD). The aim of this study was to examine whether different types of adipose tissue depot may play differential roles in the progression of CAD. Consecutive 174 patients who underwent both computed tomography (CT) and echocardiography were analyzed. Cardiac and abdominal CT scans were performed to mea...

The role of epicardial and perivascular adipose tissue in the pathophysiology of cardiovascular disease

Obesity, insulin resistance and the metabolic syndrome, are characterized by expansion and inflammation of adipose tissue, including the depots surrounding the heart and the blood vessels. Epicardial adipose tissue (EAT) is a visceral thoracic fat depot located along the large coronary arteries and on the surface of the ventricles and the apex of the heart, whereas perivascular adipose tissue (...

Can epicardial adipose tissue predict coronary artery plaque?